U-Harley Street uvame ukubizwa ngokuthi “ILondon Medical” ngenxa yokuthi inokunye okugxilwe kakhulu kobuchwepheshe bezokwelapha emhlabeni. Ngesithunzi sesikhathi eside njengesikhungo sobungcweti bezokwelapha ezizimele, Ukuhlangana kwasekuqaleni kuka-Harley Street nemithi kungalandelelwa emuva emuva 1860 lapho odokotela abaningi bethuthela endaweni ngenxa yendawo emaphakathi kanye nokuba seduze kweziteshi zesitimela ezinkulu, njengeKings Cross, I-St Pancras ne-Marylebone. Kusukela ngekhulu leshumi nesishiyagalolunye inani lodokotela, izibhedlela, imitholampilo yokuhlinza amehlo nezinye izinhlangano zezokwelapha ezisendaweni nasezindaweni ezizungeze u-Harley Street yenyuke kakhulu. Kwakukhona nxazonke 20 odokotela abasebenza endaweni e 1860 futhi ukwanda okuphindwe kashumi kwabhalwa ngu 1914 lapho isibalo sikhuphuka 200. Ezinye izengezo ezimbili ezamukelekile kule ndawo eziphinde zathuthukisa isithunzi sendawo kwakuyi-Medical Society yaseLondon, evulwe kuChandos Street ku 1873 kanye neRoyal Society of Medicine eyaqala ngo 1912 ku-Wimpole Street.Eminyakeni edlule u-Harley Street ube yikhaya lochwepheshe bezokwelapha abaningi abadumile. Sir Henry Thompson, udokotela ohlinzayo omkhulu waseBrithani kanye ne-polymath, wasebenza endaweni ngeminyaka yawo-1870s futhi waqhubeka waqokwa njengodokotela ohlinzayo omkhulu weNkosi yaseBrussels.Udokotela u-Edward Bach wayezilolongela kusukela ku-Harley Street ngeminyaka yawo-1920 ngaphambi kokuthuthela eLondon Homeopathic Hospital wabe esethuthukisa i-Bach Flower Remedies namanje edumile namuhla. Ngokusobala izikhathi zishintshile kusukela ngekhulu leshumi nesishiyagalolunye lapho odokotela bebezosungula indawo yokuhlinza emzini wabo futhi bazihlelele izikhathi zabo zokubonana futhi u-Harley Street uyaqhubeka nokuchuma njengesikhungo sazo zonke izinto zokwelapha.. Akudingekile ukusho ukuthi imitholampilo etholakala lapha inikeza ubuchwepheshe bamuva kanye nobuchwepheshe bezokwelapha obuhamba phambili bezwe. Namuhla sekuphelile 3,000 abantu abaqashwe endaweni ehlinzeka ngezinsiza eziningi zezempilo, kusukela emuthini ohambisanayo kuya ekuhlinzeni ngepulasitiki. Ngakho-ke noma ngabe ufuna ukuhlinzwa kwamehlo nge-laser e-London noma udinga nje ukubhalisa ku-GP uqinisekile ukuthi uthola okudingayo lapha i-Harley Street yenza indawo efiseleka kakhulu ongaprakthiza kuyo futhi indawo iyaqhubeka nokuheha inqwaba yabantu. odokotela abaphezulu, kusukela kodokotela abahlinza amehlo nodokotela kuya kodokotela bengqondo nodokotela abahlinzayo bepulasitiki. Uma udinga ukufika ku-Harley Street ukuze uthole i-aphoyintimenti khona-ke unezinketho eziningi ongakhetha kuzo. Uma ubamba ishubhu ungehla ku-Bond Street noma e-Oxford Circus uye endaweni eseningizimu, kuyilapho i-Regents Park kanye ne-Great Portland Street ilele enyakatho ukuze ukwazi ukubamba kalula ishubhu ukuze ilingane ncamashi nalapho uya khona.. Yini enye, Iziteshi zikaloliwe i-Marylebone ne-Euston zombili ziseduze futhi izindawo zokupaka izimoto e-Portland Place naku-Harley Street zenza ukuphila kube lula kulabo abafika ngemoto..